Nanosistemas inovadores com reposicionamento de fármacos para o tratamento de doenças periodontais

This project is framed within the Medical Biotechnology scientific area and Health-related Biotechnology subarea, given the intended objective to develop an innovative therapeutic approach for Periodontal Diseases (PDs). Briefly, the project aims the development, characterization and proof-of-concept validation of a novel perioceutic nanosystem that conjoins antibacterial bimetallic oxide nanoparticles delivering a repurposed tetracycline, further associated with a monoclonal antibody (tocilizumab). Research development reaches hand of knowledge from distinct domains of specialization, namely materials engineering, nanotechnology, pharmacology, and immunology, outreaching to a technological development that entails into a groundbreaking and innovative therapeutic approach for PDs.